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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1162014Generated: October 28, 2026

{[(2R)-1-Ethylpyrrolidin-2-yl]methyl}(5-nitro-1-benzofuran-7-yl)amine → N7-{[(2R)-1-Ethylpyrrolidin-2-yl]methyl}-1-benzofuran-5,7-diamine

https://huagongshe.com/reaction/1162014

Reaction equation

Participants

RoleNameHCIDCharge
Reactant{[(2R)-1-Ethylpyrrolidin-2-yl]methyl}(5-nitro-1-benzofuran-7-yl)amineHCID 66893445—
ReactantN7-(2-Morpholin-4-ylethyl)-1-benzofuran-5,7-diamineHCID 86058078—
ProductN7-{[(2R)-1-Ethylpyrrolidin-2-yl]methyl}-1-benzofuran-5,7-diamineHCID 86609635—

Reaction Steps

The title compound was prepared according to the procedure described for Intermediate 28 using {[(2R)-1-ethylpyrrolidin-2-yl]methyl}(5-nitro-1-benzofuran-7-yl)amine (Intermediate 37). The obtained product was used directly in the subsequent reaction.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07820675B2
Source datasetuspto-grants-2010_10
ORD IDord-f64d002371ad4594be2a520046bdf413
Source noteuspto-grants-2010_10