Benzenesulfonic Acid → HCID 66892329, compound

HRID 1162074Notes

Reaction equation

HRID 1162074 reaction equation
CO[C:3]1[CH:8]=[CH:7][C:6](C)=[CH:5][C:4]=1[S:10]([C:13]1[CH:14]=[C:15]([C:22]([O:24][CH3:25])=[O:23])[C:16]2[O:20][CH2:19][CH2:18][C:17]=2[CH:21]=1)(=[O:12])=[O:11].O1C2C(C(OC)=O)=CC=CC=2CC1.C1(S(O)(=O)=O)C=CC=CC=1>>[C:4]1([S:10]([C:13]2[CH:14]=[C:15]([C:22]([O:24][CH3:25])=[O:23])[C:16]3[O:20][CH2:19][CH2:18][C:17]=3[CH:21]=2)(=[O:12])=[O:11])[CH:3]=[CH:8][CH:7]=[CH:6][CH:5]=1

Participants

4

Reactant 3

HCID 7371Benzenesulfonic AcidHCID 15062252Methyl 2,3-dihydrobenzofuran-7-carboxylate2×HCID 66893378HCID 66893378, compound

Product 1

HCID 66892329HCID 66892329, compound

Procedure

The title compound was prepared according to the procedure of Intermediate 66 starting from methyl 2,3-dihydro-1-benzofuran-7-carboxylate (1 g, 5.6 mmol; Intermediate 65) and benzenesulfonic acid (0.89 g, 5.6 mmol). Yield: 882 mg (49%). MS (ESI+) for C16H14O5S m/z 319 (M+H)+.

Sources & evidence

ORD record
ord-fee4e1cac5f94de897e8e497b8d06073
Source dataset
uspto-grants-2010_10
Patent number
US07820675B2

Reaction notes

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