HCID 66892329, compound → HCID 66892653, compound

HRID 1162075Notes

Reaction equation

HRID 1162075 reaction equation
CO[C:3]1[CH:8]=[CH:7][C:6](C)=[CH:5][C:4]=1[S:10]([C:13]1[CH:14]=[C:15]([C:22]([O:24][CH3:25])=[O:23])[C:16]2[O:20][CH:19]=[CH:18][C:17]=2[CH:21]=1)(=[O:12])=[O:11].C1(S(C2C=C(C(OC)=O)C3OCCC=3C=2)(=O)=O)C=CC=CC=1>>[C:4]1([S:10]([C:13]2[CH:14]=[C:15]([C:22]([O:24][CH3:25])=[O:23])[C:16]3[O:20][CH:19]=[CH:18][C:17]=3[CH:21]=2)(=[O:12])=[O:11])[CH:3]=[CH:8][CH:7]=[CH:6][CH:5]=1

Participants

3

Reactant 2

HCID 66892329HCID 66892329, compoundHCID 66893431HCID 66893431, compound

Product 1

HCID 66892653HCID 66892653, compound

Procedure

The title compound was prepared according to the procedure of Intermediate 67 starting from methyl 5-(phenylsulfonyl)-2,3-dihydro-1-benzofuran-7-carboxylate (198 mg, 0.6 mmol; obtained in Step 1). Yield: 80 mg (41%) after purification by preparative HPLC (System F; 40-70% MeCN). MS (ESI+) for C16H14O5S m/z 317 (M+H)+.

Workup

  1. customYield: 80 mg (41%) after purification by preparative HPLC (System F; 40-70% MeCN)

Sources & evidence

ORD record
ord-6448a83ad50444f588ae493829dc4139
Source dataset
uspto-grants-2010_10
Patent number
US07820675B2

Reaction notes

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