HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Aminomethyl)-5-methylpyrazine → HCID 68648262, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Aminomethyl)-5-methylpyrazine | HCID 2756496 | — |
| Reactant | 3-Bromo-6-chloroimidazo(1,2-b)pyridazine | HCID 12872323 | — |
| Reactant | Dichloromethane methanol ammonium hydroxide | HCID 21896990 | — |
| Product | HCID 68648262 | HCID 68648262 | — |
Reaction Steps
Prepared from 3-bromo-6-chloroimidazo[1,2-b]pyridazine and (5-methylpyrazin-2-yl)methanamine according to general procedure 1 providing the intermediate (64 mg, 34%) as a yellow solid: Rf=0.67 (CH2Cl2/MeOH/NH4OH, 160:18:2); 1H NMR (500 MHz, CD3OD) δ 8.69 (s, 1H), 8.47 (s, 1H), 7.60 (d, J=9.7 Hz, 1H), 7.39 (s, 1H), 6.79 (d, J=9.7 Hz, 1H), 4.66 (s, 2H), 2.53 (s, 3H); ES-MS: (M+H)=319, 321 m/z.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07820670B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-d7d49a944a3f4fa0b14cece5389870e4 |
| Source note | uspto-grants-2010_10 |