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HRID1162240

反应详情

EQUATION

反应方程式

HRID 1162240 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)[C@@H](C)O
HCID637514

(+)-Methyl lactate

C4H8O3

结构：Fc1cccc(Cn2ncc3cc(Nc4ncnc5cccc(F)c45)ccc32)c1
HCID68619430

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)[C@H](C)Oc1cccc2ncnc(Nc3ccc4c(cnn4Cc4cccc(F)c4)c3)c12
HCID86627836

未命名化合物

PROCEDURE

实验过程

The 5-fluoro-N-[1-(3-fluorobenzyl)-1H-indazol-5-yl]quinazolin-4-amine (2.4 g, 6.48 mmol) was reacted as in Example 5 starting material, except that (R)-methyl lactate was used instead of (s)-methyl lactate, to give methyl (2S)-2-[(4-{[1-(3-fluorobenzyl)-1H-indazol-5-yl]amino}quinazolin-5-yl)oxy]propanoate: