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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1162538Generated: October 27, 2026

Thiourea → 4-(4-Isopropyl-phenyl)-thiazol-2-ylamine

https://huagongshe.com/reaction/1162538

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThioureaHCID 2723790—
Reactant2-Bromo-1-(4-(propan-2-yl)phenyl)ethan-1-oneHCID 14042756—
SolventMethanolHCID 887—
Product4-(4-Isopropyl-phenyl)-thiazol-2-ylamineHCID 673693—

Reaction Steps

4-(4-Isopropyl-phenyl)-thiazol-2-ylamine was prepared (0.41 g) following general procedure B using 2-bromo-1-(4-isopropyl-phenyl)-ethanone (0.5 g, 2.07 mmol), thiourea (173 mg, 2.28 mmol) and MeOH (10 mL). LCMS m/z: 219 (M+1)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07820704B2
Source datasetuspto-grants-2010_10
ORD IDord-a8dfa7fcbed24e7e957d38e0de9d1715
Source noteuspto-grants-2010_10