HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butanol → Tert-butyl 2-(chlorosulfonyl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butanol | HCID 6386 | — |
| Reactant | (Chlorosulphonyl)acetyl chloride | HCID 77642 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Tert-butyl 2-(chlorosulfonyl)acetate | HCID 43350783 | — |
Reaction Steps
To a solution of t-butanol (0.3 mL) in THF (3 mL) was added 2-chlorosulfonylacetyl chloride (0.1 mL, 1.0 mmol) at room temperature for 1 h. The volatiles were removed to provide the chlorosulfonyl-acetic acid tert-butyl ester (230 mg). The crude product was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07820704B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-d7bf5b9e1c9b41ac957732f8e4b4e51a |
| Source note | uspto-grants-2010_10 |