Tetrahydrofuran → HCID 68647686, compound

Participants

Reaction Steps

2-({[4-(4-Isopropyl-phenyl)-thiazol-2-yl]-thiophen-2-ylmethyl-amino}-methyl)-benzonitrile was prepared by stirring (4-(-isopropyl-phenyl)-thiazol-2-yl)-thiophen-2-ylmethyl-amine (100 mg, 0.31 mmol), NaH (26 mg, 60%, 0.62 mmol), and 2-bromomethylbenzonitrile (72 mg, 0.372 mmol) in THF (50 mL) at room temperature. After 3 h, the reaction mixture was concentrated under high vacuum. The crude product used without purification.

Provenance & Evidence