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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1162607Generated: October 28, 2026

5-Chloro-2-thiophenecarboxylic acid → HCID 58748323, compound

https://huagongshe.com/reaction/1162607

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chloro-2-thiophenecarboxylic acidHCID 95048—
ReactantHCID 68646554HCID 68646554—
ProductHCID 58748323HCID 58748323—

Reaction Steps

1.3 Using general method D, ((R)-3-amino-pyrrolidin-1-yl)-acetic acid ethyl ester dihydrochloride was coupled with 5-chlorothiophene-2-carboxylic acid to give {(R)-3-[(5-chloro-thiophene-2-carbonyl)-amino]-pyrrolidin-1-yl}-acetic acid ethyl ester. Off-white amorphous solid. MS 317.0 ([M+H]+)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07820699B2
Source datasetuspto-grants-2010_10
ORD IDord-1a4a5a08604b45389049156c8d032f5a
Source noteuspto-grants-2010_10