HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloro-2-thiophenecarboxylic acid → HCID 58748154, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloro-2-thiophenecarboxylic acid | HCID 95048 | — |
| Reactant | (R)-(+)-1-Boc-3-aminopyrrolidine | HCID 854070 | — |
| Product | HCID 58748154 | HCID 58748154 | — |
Reaction Steps
6.1 Using general procedure D (R)-1-Boc-3-aminopyrrolidine was coupled with 5-chlorothiophene-2-carboxylic acid to give (R)-3-[(5-chloro-thiophene-2-carbonyl)-amino]-pyrrolidine-1-carboxylic acid tert-butyl ester. Yellow solid. MS 329.3 ([M−H]−)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07820699B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-fc10926032fc490681aa72deeb2fa08e |
| Source note | uspto-grants-2010_10 |