HCID 68646448, compound → HCID 42643337, compound

Participants

Reaction Steps

11.4 Using general procedure A with DMF as solvent (2S,4R)-4-[(5-chloro-thiophene-2-carbonyl)-amino]-pyrrolidine-2-carboxylic acid methyl ester hydrochloride was reacted with 2-bromo-[2-fluoro-4-(2-oxo-pyridin-1-yl)-phenyl]-acetamide to give (2S,4R)-4-[(5-chloro-thiophene-2-carbonyl)-amino]-1-{[2-fluoro-4-(2-oxo-pyridin-1-yl)-phenylcarbamoyl]-methyl}-pyrrolidine-2-carboxylic acid methyl ester. White solid. MS 533.2 ([M+H]+)

Provenance & Evidence