HCID 68646448, compound → HCID 42643276, compound

Participants

Reaction Steps

40.4 Using general procedure A with THF as solvent (3S,4R)-4-[(5-chloro-thiophene-2-carbonyl)-amino]-pyrrolidine-3-carboxylic acid ethyl ester hydrochloride was reacted with 2-bromo-[2-fluoro-4-(2-oxopyridin-1-yl)-phenyl]-acetamide to give (3S,4R)-4-[(5-chloro-thiophene-2-carbonyl)-amino]-1-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl-carbamoyl]-methyl}-pyrrolidine-3-carboxylic acid ethyl ester. Light brown solid. MS 547.2 [M+H+].

Provenance & Evidence