HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloronicotinic acid → HCID 58748150, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloronicotinic acid | HCID 79222 | — |
| Reactant | tert-Butyl (3R)-3-(aminomethyl)pyrrolidine-1-carboxylate | HCID 1515152 | — |
| Product | HCID 58748150 | HCID 58748150 | — |
Reaction Steps
63.1 Using general procedure E, (R)-3-aminomethyl-1-N-tert-butoxycarbonyl-pyrrolidine was coupled with 6-chloro-nicotinic acid to give (R)-3-{[(6-chloro-pyridine-3-carbonyl)-amino]-methyl}-pyrrolidine-1-carboxylic acid tert-butyl ester. Yellow oil. MS 340.1 ([M+H]+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07820699B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-6b52d91581bc4908870112cc8c3a13e4 |
| Source note | uspto-grants-2010_10 |