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HRID1162716

反应详情

EQUATION

反应方程式

HRID 1162716 的结构方程式

REACTANTS

反应物

2
结构：CCOC(=O)CN1C[C@H](NC(=O)c2ccc(Cl)s2)[C@@H](OC)C1
HCID58748327

未命名化合物

结构：CC(C)(C)OC(=O)C1=Nc2nc(N)sc2CC1
HCID86608840

未命名化合物

PRODUCTS

生成物

1
结构：CO[C@H]1CN(CC(=O)Nc2nc3c(s2)CCC(C(=O)OC(C)(C)C)=N3)C[C@@H]1NC(=O)c1ccc(Cl)s1
HCID86608839

未命名化合物

PROCEDURE

实验过程

94.1 In analogy to example 25.3 {(3S,4S)-3-[(5-chloro-thiophene-2-carbonyl)-amino]-4-methoxy-pyrrolidin-1-yl}-acetic acid ethyl ester (example 25.2) was reacted with 2-amino-6,7-dihydro-thiazolo[5,4]pyridine-5-carboxylic acid tert-butyl ester (CAS 365996-05-0) to give 2-(2-{(3S,4S)-3-[(5-chloro-thiophene-2-carbonyl)-amino]-4-methoxy-pyrrolidin-1-yl}-acetylamino)-6,7-dihydro-thiazolo[5,4-]pyridine-5-carboxylic acid tert-butyl ester as off-white solid. MS 556.3 ([M+H]+)