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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1163049Generated: October 28, 2026

1-(3-(Benzyloxy)-2-fluoro-6-nitrophenyl)propan-2-one → 4-fluoro-2-methyl-1H-indol-5-ol

https://huagongshe.com/reaction/1163049

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-(Benzyloxy)-2-fluoro-6-nitrophenyl)propan-2-oneHCID 11289663—
Reactant1-(2-Fluoro-3-hydroxy-6-nitrophenyl)propan-2-oneHCID 22337995—
Product4-fluoro-2-methyl-1H-indol-5-olHCID 10352036—

Reaction Steps

1-(3-Benzyloxy-2-fluoro-6-nitro-phenyl)-propan-2-one can also be converted to 1-(2-fluoro-3-hydroxy-6-nitrophenyl)-propan-2-one by the following two alternate methods.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07820814B2
Source datasetuspto-grants-2010_10
ORD IDord-ed16158532954d76acd9a1d1cf945bb5
Source noteuspto-grants-2010_10