Sodium Iodide → HCID 23111765, compound

Participants

Reaction Steps

4-(Benzyloxy)-2-hydroxybenzaldehyde (5.8 g), ethyl 4-bromobutyrate (7.1 mL), potassium carbonate (10.5 g) and sodium iodide (3.8 g) were added to N,N-dimethylformamide (50 mL), and the mixture was stirred overnight at room temperature. The mixture was poured into water and extracted with ethyl acetate. The organic layer was washed with water and brine and dried over magnesium sulfate, and the solvent was evaporated. The residue was purified by silica gel column chromatography (ethyl acetate:hexane) to give the title compound (8.2 g) as an oil.

Provenance & Evidence