HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 67274031, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1,2-Difluoro-4-nitrobenzene | HCID 123053 | — |
| Reactant | 3-Amino-1-(diphenylmethyl)azetidine | HCID 5744546 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 67274031 | HCID 67274031 | — |
Reaction Steps
A solution of 7.96 g of 1-benzhydrylazetidin-3-ylamine (33.41 mmol), 3.69 ml 3,4-difluoronitrobenzene (33.41 mmol) and 4.65 ml triethylamine (33.41 mmol)) in 50 ml ethyl acetate was stirred for 2 weeks at 60° C. The reaction was diluted with water and the product extracted with ethyl acetate. The organic layer was washed with water and brine, dried over MgSO4, filtered and evaporated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07820823B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-b0f2d4c83f3b4410b0b6ecfd2e7d8b8e |
| Source note | uspto-grants-2010_10 |