Hydrochloric Acid → 2-Cyclohexylbenzenamine

HRID 1163385Notes

Reaction equation

HRID 1163385 reaction equation
C(OC(=O)[NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[CH:14]1[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1)(C)(C)C.Cl>O1CCOCC1>[CH:14]1([C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=2[NH2:7])[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 60008768(2-Cyclohexylphenyl)-carbamic acid tert-butyl ester

Product 1

HCID 4078992-Cyclohexylbenzenamine

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

The carbamate obtained as above was treated with 4 M HCl in dioxane following the procedure described in Example 80 to afford 2-cyclohexylphenylamine as a hydrochloride salt.

Sources & evidence

ORD record
ord-2179292dc3084f5db63be0bc974bcaf5
Source dataset
uspto-grants-2010_10
Patent number
US07820821B2

Reaction notes

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