HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Diethylphenyl isothiocyanate → 2-(2,6-diethylphenylamino)-3H-benzimidazole-5-carboxylic acid (1H-indazol-6-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Diethylphenyl isothiocyanate | HCID 141193 | — |
| Reactant | HCID 59522617 | HCID 59522617 | — |
| Solvent | tetrahydrofuran N,N-dimethylformamide | HCID 21974620 | — |
| Product | 2-(2,6-diethylphenylamino)-3H-benzimidazole-5-carboxylic acid (1H-indazol-6-yl)-amide | HCID 58970720 | — |
Reaction Steps
A solution of 1,3-diethyl-2-isothiocyanatobenzene (0.5 mmol) in 1:1 DMF/THF (2 mL) was reacted with 3,4-diamino-N-(1H-indazol-6-yl)-benzamide (0.5 mmol; see Example 25) according to general procedure B to yield 2-(2,6-diethylphenylamino)-3H-benzimidazole-5-carboxylic acid (1H-indazol-6-yl)-amide. MS: m/z 425 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07820821B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-31fc3a0d52c34a71aaa2fa1ad72ab8b3 |
| Source note | uspto-grants-2010_10 |