Hydrochloric Acid → HCID 66758828, compound

HRID 1163622Notes

Reaction equation

HRID 1163622 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]2[N:14]=[C:13]([NH:15][C:16]3[CH:21]=[CH:20][C:19]([NH2:22])=[CH:18][CH:17]=3)[C:12]([F:23])=[CH:11][N:10]=2)=[CH:4][CH:3]=1.[ClH:24]>O1CCOCC1>[ClH:24].[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]2[N:14]=[C:13]([NH:15][C:16]3[CH:21]=[CH:20][C:19]([NH2:22])=[CH:18][CH:17]=3)[C:12]([F:23])=[CH:11][N:10]=2)=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 22060450HCID 22060450, compound

Product 1

HCID 66758828HCID 66758828, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

N2,N4-Bis(4-aminophenyl)-5-fluoro-2,4-pyrimidinediamine was treated with 2 equivalents of HCl in dioxane. The volatiles were removed under reduced pressure to give N2,N4-bis(4-aminophenyl)-5-fluoro-2,4-pyrimidinediamine Hydrogen Chloride Salt. LCMS: ret. time: 11.15 min.; purity: 100%; MS (m/e): 311.09 (MH+).

Workup

  1. customThe volatiles were removed under reduced pressure

Sources & evidence

ORD record
ord-ec2bffb6a9bc4634850c8c18cc3447e7
Source dataset
uspto-grants-2010_10
Patent number
US07820819B2

Reaction notes

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