Ethanol → HCID 20438511, compound

Participants

Reaction Steps

8.4 g. of 2-amino-pyrroline and 19.2 g. of ethyl 2-formyl-phenyl-acetate are heated in 150 ml. ethanol for 5 hours and the reaction mixture is evaporated. The residue is treated with petrol ether, the obtained crystals are filtered. 15.9 g. (75%) of a mixture of 3-phenyl-2-oxo-2,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine and 3-phenyl-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine are obtained, melting slowly between 98° to 120° C.

Provenance & Evidence