反应详情

N-Bromosuccinimide (6.56 g) and 2,2'-azobisisobutyronitrile (100 mg) were added to a solution of 2-methoxyphenyl 2-methoxy-3-methylphenyl ether (9.0 g) in benzene (100 ml), and the mixture was refluxed under heating for 2 hrs. The reaction mixture was evaporated, and water was added to the residue. The mixture was extracted with diethyl ether, and the extract was washed with water, dried over magnesium sulfate and then evaporated to give oily residue of 2-methoxyphenyl 2-methoxy-3-bromomethylphenyl ether (12.10 g).

1. temperaturethe mixture was refluxed
2. temperatureunder heating for 2 hrs
3. customThe reaction mixture was evaporated
4. additionwater was added to the residue
5. extractionThe mixture was extracted with diethyl ether
6. washthe extract was washed with water
7. dry with materialdried over magnesium sulfate
8. customevaporated