Acetic Acid → HCID 20513509, compound

HRID 1164006Notes

Reaction equation

HRID 1164006 reaction equation
[CH3:1][O:2][C:3]1[C:8]([O:9][C:10]2[CH:15]=[CH:14][C:13]([Cl:16])=[CH:12][CH:11]=2)=[CH:7][CH:6]=[CH:5][C:4]=1CC#N.Cl.[C:21]([OH:24])(=[O:23])[CH3:22]>>[CH3:1][O:2][C:3]1[C:8]([O:9][C:10]2[CH:11]=[CH:12][C:13]([Cl:16])=[CH:14][CH:15]=2)=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:22][C:21]([OH:24])=[O:23]

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 313Hydrochloric AcidHCID 20513481HCID 20513481, compound

Product 1

HCID 20513509HCID 20513509, compound

Procedure

2-[2-Methoxy-3-(4-chlorophenoxy)phenyl]acetonitrile (11.8 g), glacial acetic acid (50 ml) and conc. hydrochloric acid (25 ml) were treated in a similar manner to that of Example 5-(4) to give oily 2-[2-methoxy-3-(4-chlorophenoxy)phenyl]acetic acid (6.7 g).

Sources & evidence

ORD record
ord-86c202c8778149649bdfabe15c81cf3a
Source dataset
uspto-grants-1983_01
Patent number
US04367238

Reaction notes

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