Hydrochloric Acid → 6-(3-Chlorophenoxy)-o-cresol
Reaction equation
[CH3:1][C:2]1[CH:8]=[CH:7][CH:6]=[C:5]([O:9][C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([Cl:16])[CH:11]=2)[C:3]=1N.Cl.[OH2:18]>>[Cl:16][C:12]1[CH:11]=[C:10]([CH:15]=[CH:14][CH:13]=1)[O:9][C:5]1[CH:6]=[CH:7][CH:8]=[C:2]([CH3:1])[C:3]=1[OH:18]Participants
4
Procedure
A mixture of 2-methyl-6-(3-chlorophenoxy)aniline (40 g) and conc. hydrochloric acid (36 ml) in water (125 ml) was treated in a similar manner to that of Example 6-(1) to give oily 6-(3-chlorophenoxy)-o-cresol (13.9 g)
Workup
- additionwas treated in a similar manner to that of Example 6-(1)
Sources & evidence
- ORD record
- ord-2b710e4c10684ffbacf46a40a329ef03
- Source dataset
- uspto-grants-1983_01
- Patent number
- US04367238
Reaction notes
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