HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[2-Methoxy-3-(3-chlorophenoxy)phenyl]acetic acid → 2-[2-Hydroxy-3-(3-chlorophenoxy)phenyl]acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[2-Methoxy-3-(3-chlorophenoxy)phenyl]acetic acid | HCID 20513488 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Solvent | Hydrogen iodide | HCID 24841 | — |
| Product | 2-[2-Hydroxy-3-(3-chlorophenoxy)phenyl]acetic acid | HCID 13066683 | 48.3% |
Reaction Steps
A solution of 2-[2-methoxy-3-(3-chlorophenoxy)phenyl]acetic acid (10 g) in acetic anhydride (30 ml) and 48% hydriodic acid (60 ml) were treated in a similar manner to that of Example 6-(6) to give 2-[2-hydroxy-3-(3-chlorophenoxy)phenyl]acetic acid (4.6 g). mp 99°-102° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04367238 |
| Source dataset | uspto-grants-1983_01 |
| ORD ID | ord-ccd669f8e41a4e79a72dc8c290949f83 |
| Source note | uspto-grants-1983_01 |