HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 2-[2-Methoxy-3-(2-chlorophenoxy)phenyl]butyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Ethyl 2-cyano-2-[2-methoxy-3-(2-chlorophenoxy)phenyl]butyrate | HCID 20513442 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-[2-Methoxy-3-(2-chlorophenoxy)phenyl]butyric acid | HCID 20513467 | 82% |
Reaction Steps
A mixture of ethyl 2-cyano-2-[2-methoxy-3-(2-chlorophenoxy)phenyl]butyrate (5.9 g) and potassium hydroxide (4.5 g) in ethanol (80 ml) and water (40 ml) was treated in a similar manner to that of Example 14-(7). The resultant residue was washed with n-hexane and dried to give 2-[2-methoxy-3-(2-chlorophenoxy)phenyl]butyric acid (4.15 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04367238 |
| Source dataset | uspto-grants-1983_01 |
| ORD ID | ord-e2fe17eea1e04167b2c887aacd398dcf |
| Source note | uspto-grants-1983_01 |