Tert-Butylamine → HCID 13138209, compound

HRID 1164291Notes

Reaction equation

HRID 1164291 reaction equation
[N:1]([C:4]1[CH:5]=[C:6]([S:10]([NH:13][C:14]([NH:16][C:17]2[N:22]=[C:21]([O:23][CH3:24])[CH:20]=[C:19]([CH3:25])[N:18]=2)=[O:15])(=[O:12])=[O:11])[CH:7]=[CH:8][CH:9]=1)=[C:2]=[O:3].[C:26]([NH2:30])([CH3:29])([CH3:28])[CH3:27]>>[C:26]([NH:30][C:2](=[O:3])[NH:1][C:4]1[CH:5]=[C:6]([S:10]([NH:13][C:14]([NH:16][C:17]2[N:22]=[C:21]([O:23][CH3:24])[CH:20]=[C:19]([CH3:25])[N:18]=2)=[O:15])(=[O:12])=[O:11])[CH:7]=[CH:8][CH:9]=1)([CH3:29])([CH3:28])[CH3:27]

Participants

3

Reactant 2

HCID 6385Tert-ButylamineHCID 204558693-isocyanato-N-[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]benzenesulfonamide

Product 1

HCID 13138209HCID 13138209, compound

Procedure

To a solution of 3-isocyanato-N-[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]benzenesulfonamide prepared as in Example 3 was added 0.8 g of tert-butylamine at ambient temperature with stirring. After sixteen hours, filtration of the reaction mixture and evaporation of the filtrate yielded the desired product which after trituration with ethyl ether and isolation by filtration melted at 137°-145°.

Workup

  1. waitAfter sixteen hours
  2. filtrationfiltration of the reaction mixture and evaporation of the filtrate

Sources & evidence

ORD record
ord-d35679ed29bf42f1999f8ca4644b107d
Source dataset
uspto-grants-1983_01
Patent number
US04369058

Reaction notes

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