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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1164304Generated: November 3, 2026

Tetrahydrofuran → HCID 12726273, compound

https://huagongshe.com/reaction/1164304

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantHCID 20511711HCID 20511711—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 12726273HCID 12726273—

Reaction Steps

2.0 g. of 1-(p-benzyloxybenzoyl)-2-pyrrolidinone are hydrogenated in 20 ml. of absolute tetrahydrofuran and 20 ml. of absolute methanol over 300 mg. of palladium/carbon (5%) under atmospheric pressure and at room temperature. The catalyst is filtered off, the filtrate is concentrated and the residue is triturated with diethyl ether. After filtration, there is obtained 1-(p-hydroxybenzoyl)-2-pyrrolidinone, having a melting point of 179°-182° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04369139
Source datasetuspto-grants-1983_01
ORD IDord-0e94fc9c62a64225856e93ff386f4b7b
Source noteuspto-grants-1983_01