HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → Piperazine, 1-(2-ethylphenyl)-4-((3,4,5-trimethoxyphenyl)methyl)-, dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5-(Chloromethyl)-1,2,3-trimethoxybenzene | HCID 77448 | — |
| Reactant | 1-(2-Ethylphenyl)piperazine | HCID 2736460 | — |
| Product | Piperazine, 1-(2-ethylphenyl)-4-((3,4,5-trimethoxyphenyl)methyl)-, dihydrochloride | HCID 3062135 | 76.5% |
Reaction Steps
8.3 g of 3,4,5-trimethoxybenzyl chloride and 3.8 g of N-(2-ethylphenyl)-piperazine and 3.5 g of K2CO3 are reacted and processed according to example 2. 6.5 g of N-(3,4,5-trimethoxy-benzyl)-N'-(2-ethylphenyl)-piperazine dihydrochloride is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04370329 |
| Source dataset | uspto-grants-1983_01 |
| ORD ID | ord-72959b2f83ef4f92acb3676ba8878eb7 |
| Source note | uspto-grants-1983_01 |