HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → Piperazine, 1-(4-methoxyphenyl)-4-((3,4,5-trimethoxyphenyl)methyl)-, dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5-(Chloromethyl)-1,2,3-trimethoxybenzene | HCID 77448 | — |
| Reactant | 1-(4-Methoxyphenyl)piperazine | HCID 269722 | — |
| Product | Piperazine, 1-(4-methoxyphenyl)-4-((3,4,5-trimethoxyphenyl)methyl)-, dihydrochloride | HCID 3062144 | 101.1% |
Reaction Steps
3.85 g of N-(4-methoxyphenyl)-piperazine, 4.33 g of 3,4,5-trimethoxybenzyl chloride and 3.5 g of K2CO3 are reacted and processed according to example 2. 4.5 g of N-(3,4,5-trimethoxy-benzyl)-N'-(4-methoxyphenyl)-piperazine dihydrochloride is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04370329 |
| Source dataset | uspto-grants-1983_01 |
| ORD ID | ord-79cda333e2e64d4db2f74f68b5e233b8 |
| Source note | uspto-grants-1983_01 |