HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → Phenol, 4-(4-((3,4,5-trimethoxyphenyl)methyl)-1-piperazinyl)-, monohydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5-(Chloromethyl)-1,2,3-trimethoxybenzene | HCID 77448 | — |
| Reactant | p-(1-Piperazinyl)phenol | HCID 92467 | — |
| Product | Phenol, 4-(4-((3,4,5-trimethoxyphenyl)methyl)-1-piperazinyl)-, monohydrochloride | HCID 3062140 | 54.2% |
Reaction Steps
8.3 g of 3,4,5-trimethoxybenzyl chloride and 3.5 g of N-(4-hydroxyphenyl)-piperazine and 3.5 g of K2CO3 are reacted and processed according to example 2. 4.2 g of N-(3,4,5-trimethoxy-benzyl)-N'-(4-hydroxyphenyl)-piperazine hydrochloride is obtained. Mp.: 268° C. (decomposition).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04370330 |
| Source dataset | uspto-grants-1983_01 |
| ORD ID | ord-5e4ce0fa57ac4c5cb8a6f3749a74713d |
| Source note | uspto-grants-1983_01 |