HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylene Glycol → N-[6-(2-Methyl-1,3-dioxolan-2-yl)hexyl]phthalimide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylene Glycol | HCID 174 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | 2-(7-Oxooctyl)isoindoline-1,3-dione | HCID 20511306 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | N-[6-(2-Methyl-1,3-dioxolan-2-yl)hexyl]phthalimide | HCID 20511312 | — |
Reaction Steps
A mixture of 142.0 g (0.52 mole) of N-(7-oxooctyl)phthalimide, 60 ml of ethylene glycol, 5.80 g of p-toluenesulfonic acid and 290 ml of benzene was refluxed overnight using a Dean-Stark trap to collect the azeotrope. The reaction was cooled, treated with 2 N NaOH solution, the organic layer separated, dried over anhydrous potassium carbonate, filtered and stripped to give 125.25 g of orange oil, 76% pure by gc (SE-30, 90°-280°@16°/min).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04370335 |
| Source dataset | uspto-grants-1983_01 |
| ORD ID | ord-68ba29fde0bd46918092e069cfd91ec4 |
| Source note | uspto-grants-1983_01 |