反应详情

4,5-Dimethoxyphthalaldehydic acid (10 g.) and hydrazine hydrate (2.4 ml.) in ethanol (150 ml.) were heated under reflux for 20 hours during which time a white crystalline solid formed. The mixture was cooled in an ice bath, filtered and the resulting product dried to give crude 6,7-dimethoxyphthalazin-1-one (7 g.). A sample was crystallized from water yielding colorless needles, m.p. 254°-256° C.

1. temperatureunder reflux for 20 hours during which time a white crystalline solid
2. customformed
3. temperatureThe mixture was cooled in an ice bath
4. filtrationfiltered
5. customthe resulting product dried