反应详情

温度

25 °C

A mixture of 2,3,5,6-tetrafluorotoluene (1.7 g), N-bromosuccinimide (1.9 g), dry carbon tetrachloride (10 ml) and benzoyl peroxide (0.01 g) was heated at the reflux temperature for 20 hours, cooled to the ambient temperature (ca.25° C.) filtered and the filtrate diluted with diethyl ether. The ethereal solution was washed with water, dried over anhydrous magnesium sulphate and concentrated by evaporation of the solvents to yield 2,3,5,6-tetrafluorobenzyl bromide as a mobile colourless oil.

1. temperaturewas heated at the reflux temperature for 20 hours
2. filtrationfiltered
3. additionthe filtrate diluted with diethyl ether
4. washThe ethereal solution was washed with water
5. dry with materialdried over anhydrous magnesium sulphate
6. concentrationconcentrated by evaporation of the solvents