Benzyl Bromide → HCID 20511501, compound

HRID 1164657Notes

Reaction equation

HRID 1164657 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C:3]1=[S:8].[CH2:9]([Br:16])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>CC(C)=O>[Br-:16].[CH2:9]([S:8][C:3]1[CH2:4][CH2:5][CH2:6][CH2:7][N+:2]=1[CH3:1])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

4

Reactant 2

HCID 7498Benzyl BromideHCID 1232942-Piperidinethione, 1-methyl-

Product 1

HCID 20511501HCID 20511501, compoundYield 63.7%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

1-Methyl-2-piperidothione (1.29 g) was dissolved in acetone (10 ml) and treated with benzyl bromide (1.7 g). After allowing the mixture to stand for 3 hours at room temperature a solid formed and was filtered off, washed with acetone, and dried to give the title compound (1.9 g) mp 168°-7° C. (Found: C, 52.5; H, 6.3; N, 4.8. C13H18BrNS requires C, 52.0; H, 6.0; N, 4.7%).

Workup

  1. customa solid formed
  2. filtrationwas filtered off
  3. washwashed with acetone
  4. customdried

Sources & evidence

ORD record
ord-4464b47668924d9c9c8300e7c132ab9f
Source dataset
uspto-grants-1983_01
Patent number
US04370477

Reaction notes

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