Bis(p-methoxyphenyl) telluroxide → 5-Cholesten-3beta-thiol benzoate

Participants

Reaction Steps

5-Cholesten-3β-ol-dithionobenzoate (130 mg, 0.25 mmol) was reacted with bis-(p-methoxyphenyl)-telluroxide for 27 h. 5-Cholesten-3β-thiol-benzoate (88 mg, 70%), m.p. 160°-162° was obtained after p.l.c. (petroleum ether-ethyl acetate 20:1). The product obtained was recrystallised from ethyl acetate (65 mg, 52%), m.p. 164.5-166 (lit., 167°), νmax. (CCl4) 2800,2750,1670,1550,1250,1210,1180,920,865,810-740 (broad) and 700 cm-1, m/e 506 (M+ weak), 369, and 368 (100%).

Provenance & Evidence