反应详情

To a suspension of 0.4 g of the product of Example 4 and 0.46 g of phenyl(4-methoxy-6-methylpyrimidin-2-yl)carbamate in 10 ml of dry acetonitrile was added 0.25 g of DBU. The suspension was stirred for about two hours at room temperature, then diluted with excess water and filtered. The filtrate was acidified with concentrated hydrochloric acid to yield a precipitate. After filtration, the residue was washed with excess water and suction-dried to yield 0.35 g of the subject compound, m.p. 178° to 179° C.;

1. filtrationfiltered
2. customto yield a precipitate
3. filtrationAfter filtration
4. washthe residue was washed with excess water
5. customsuction-dried