HRID1164771

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCCCCCCCOc1ccc(-c2ccc(C(=O)Cl)cc2)cc1Cl

HCID19024225

未命名化合物

HCID45108312

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCOc1ccc(-c2ccc(C(=O)Oc3ccc(O[C@H](C)C(=O)OCCCC)cc3)cc2)cc1Cl

HCID54561695

未命名化合物

收率 15%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID263

1-Butanol

C4H10O

PROCEDURE

实验过程

This was prepared by the methods of Examples 2(b) and 2(c) using butanol instead of propanol and using 4-(3-chloro-4-octoxyphenyl)benzoyl chloride and Butyl (R)-2-(4-hydroxyphenoxy)propanoate (BHPP) in place of the OPBC and PHPTB used in Example 2(c), (yield 15%, SOR: +16°). The results of IR, 1H-NMR and mass spectroscopy and elemental analysis were consistent with the assigned structure.

WORKUP

后处理

customused in Example 2(c), (yield 15%, SOR: +16°)
customThe results of IR, 1H-NMR and mass spectroscopy and elemental analysis

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1c4cc12767284f63b88dbba1b5afa74c
来源数据集: uspto-grants-1990_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04906402
来源说明: uspto-grants-1990_03

反应 SMILES

[Cl:1][C:2]1[CH:3]=[C:4]([C:17]2[CH:25]=[CH:24][C:20]([C:21](Cl)=[O:22])=[CH:19][CH:18]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[OH:26][C:27]1[CH:42]=[CH:41][C:30]([O:31][C@H:32]([CH3:40])[C:33]([O:35][CH2:36][CH2:37][CH2:38][CH3:39])=[O:34])=[CH:29][CH:28]=1>C(O)CCC>[Cl:1][C:2]1[CH:3]=[C:4]([C:17]2[CH:25]=[CH:24][C:20]([C:21]([O:26][C:27]3[CH:28]=[CH:29][C:30]([O:31][C@H:32]([CH3:40])[C:33]([O:35][CH2:36][CH2:37][CH2:38][CH3:39])=[O:34])=[CH:41][CH:42]=3)=[O:22])=[CH:19][CH:18]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]