4-(3-Chloro-4-octoxyphenyl)benzoyl chloride → Butyl (R)-2-(4-[4-(3-chloro-4-octyloxyphenyl)phenylcarbonyloxy]phenoxy)propanoate

Participants

Reaction Steps

This was prepared by the methods of Examples 2(b) and 2(c) using butanol instead of propanol and using 4-(3-chloro-4-octoxyphenyl)benzoyl chloride and Butyl (R)-2-(4-hydroxyphenoxy)propanoate (BHPP) in place of the OPBC and PHPTB used in Example 2(c), (yield 15%, SOR: +16°). The results of IR, 1H-NMR and mass spectroscopy and elemental analysis were consistent with the assigned structure.

Provenance & Evidence