HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-2-(tetrazolo[1,5-a]pyrid 6-yl)oxirane → HCID 18637940, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-2-(tetrazolo[1,5-a]pyrid 6-yl)oxirane | HCID 13090314 | — |
| Reactant | 2-(3-Amino-3-methylbutyl)phenol | HCID 19863683 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 18637940 | HCID 18637940 | — |
Reaction Steps
A solution of 156 mg (1.46 mmol) of (R)-2-(tetrazolo[1,5-a]pyrid-6-yl)oxirane and 170 ml of 2-amino-2-methyl-4-(2-hydroxyphenyl)butane in 15 ml of absolute ethanol is heated at reflux for 6 hours. The reaction mixture is concentrated and the residue chromatographed on silica gel to give the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04906645 |
| Source dataset | uspto-grants-1990_03 |
| ORD ID | ord-58a67f93f3ad45e68a3671795e824064 |
| Source note | uspto-grants-1990_03 |