Methylamine → HCID 70358956, compound

HRID 1164913Notes

Reaction equation

HRID 1164913 reaction equation
[CH:1]([NH:4][S:5]([C:8]1(Cl)[NH:12][C:11]([Cl:13])=[CH:10][S:9]1)(=[O:7])=[O:6])([CH3:3])[CH3:2].[CH3:15][NH2:16]>>[CH:1]([N:4]([NH:16][CH3:15])[S:5]([C:8]1[S:9][CH:10]=[C:11]([Cl:13])[N:12]=1)(=[O:7])=[O:6])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 6329MethylamineHCID 22164319HCID 22164319, compound

Product 1

HCID 70358956HCID 70358956, compoundYield 78%

Procedure

In analogy to Example 5, the N-isopropyl-2-N-methylamino-4-chlorothiazole-sulphonamide was prepared by reacting N-isopropyl-2,4-dichlorothiazole-sulphonamide from Example 3 with 30% strength aqueous methylamine solution. Following recrystallization from toluene, the product of m.p. 187°-8° C. was obtained in a yield of 78% of the theoretical yield.

Workup

  1. customrecrystallization from toluene
  2. customthe product of m.p. 187°-8° C. was obtained in a yield of 78% of the theoretical yield

Sources & evidence

ORD record
ord-7d636454018f4059bb8bb05f801dfa44
Source dataset
uspto-grants-1990_03
Patent number
US04906650

Reaction notes

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