Benzaldehyde → (1-Benzylpyrrolidin-3-yl)methanol

HRID 1164945Notes

Reaction equation

HRID 1164945 reaction equation
[NH:1]1[CH2:5][CH2:4][CH:3]([CH2:6][OH:7])[CH2:2]1.[CH:8](=O)[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[C:9]1([CH2:8][N:1]2[CH2:5][CH2:4][CH:3]([CH2:6][OH:7])[CH2:2]2)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 240BenzaldehydeHCID 13400657(Pyrrolidin-3-yl)methanol

Product 1

HCID 5176654(1-Benzylpyrrolidin-3-yl)methanol

Procedure

In a manner similar to Preparation 7 react 3-pyrrolidinemethanol with benzaldehyde to obtain the title compound.

Workup

  1. customIn a manner similar to Preparation 7

Sources & evidence

ORD record
ord-07e294a6f6d8414dab73d46786ea4aff
Source dataset
uspto-grants-1990_03
Patent number
US04906634

Reaction notes

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