Benzylamine, N-octyl- → HCID 19863379, compound

HRID 1164951Notes

Reaction equation

HRID 1164951 reaction equation
[CH2:1]([NH:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[N+:17]([C:20]1[CH:25]=[CH:24][C:23]([N:26]([CH2:35][CH3:36])[C:27]([CH:29]2[CH2:31][CH:30]2[C:32](Cl)=[O:33])=[O:28])=[CH:22][CH:21]=1)([O-:19])=[O:18].C(Cl)(=O)C(Cl)=O.S(Cl)(Cl)=O>C(Cl)Cl>[CH2:35]([N:26]([C:23]1[CH:24]=[CH:25][C:20]([N+:17]([O-:19])=[O:18])=[CH:21][CH:22]=1)[C:27]([CH:29]1[CH2:31][CH:30]1[C:32]([N:9]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8])[CH2:10][C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1)=[O:33])=[O:28])[CH3:36]

Participants

6

Reactant 4

HCID 15464Benzylamine, N-octyl-HCID 24386Thionyl ChlorideHCID 65578Oxalyl chlorideHCID 19863422HCID 19863422, compound

Product 1

HCID 19863379HCID 19863379, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

In a manner similar to Preparation 32 react N-octylbenzenemethanamine with 2-[[(4-nitrophenyl)(ethyl)amino]carbonyl]cyclopropane-1-carbonyl chloride (prepared from the acid and oxalyl chloride or thionyl chloride) in methylene chloride to obtain the title compound.

Workup

  1. customIn a manner similar to Preparation 32

Sources & evidence

ORD record
ord-17894e0eafda4614a9b5d30ebac1b713
Source dataset
uspto-grants-1990_03
Patent number
US04906634

Reaction notes

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