HCID 56613324, compound → HCID 19862543, compound

Participants

Reaction Steps

Variant (b): 600 mg of 1-(4-hydroxy-3,5-di-tert.-butylbenzylamino)-2-methylmercaptoimidazole dissolved in 20 ml of ethanol are heated to 60°-70° for 2 hours while stirring with a 5-fold amount by weight of ethanol-moist Raney-nickel W2. The nickel is then removed by filtration and boiled up twice with 10 ml of ethanol each time. The combined alcoholic filtrates are evaporated, and 1-(4-hydroxy-3,5-di-tert.-butylbenzylamino)imidazole is obtained as the residue in the form of colorless crystals of m.p. 171°-174°.

Provenance & Evidence