Hydrochloric Acid → HCID 19862536, compound

HRID 1165157Notes

Reaction equation

HRID 1165157 reaction equation
C(=[N:8][N:9]1[CH:13]=[CH:12][N:11]=[C:10]1[CH:14]([CH3:16])[CH3:15])C1C=CC=CC=1.[ClH:17]>>[ClH:17].[NH2:8][N:9]1[CH:13]=[CH:12][N:11]=[C:10]1[CH:14]([CH3:16])[CH3:15]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 53972989HCID 53972989, compound

Product 1

HCID 19862536HCID 19862536, compound

Procedure

A mixture of 1 g of 1-benzylideneamino-2-isopropylimidazole and 50 ml of 1N hydrochloric acid is subjected to a steam distillation until benzaldehyde no longer passes over. The residual solution is evaporated in a vacuum. Methanol and benzene are added to the residue. The mixture is evaporated, methanol and benzene are again added and the mixture is again evaporated. Crude 1-amino-2-isopropylimidazole hydrochloride is obtained.

Workup

  1. distillationis subjected to a steam distillation until benzaldehyde
  2. customThe residual solution is evaporated in a vacuum
  3. additionMethanol and benzene are added to the residue
  4. customThe mixture is evaporated
  5. additionmethanol and benzene are again added
  6. customthe mixture is again evaporated

Sources & evidence

ORD record
ord-bf33b0070f4c4966a43da3093271f4c7
Source dataset
uspto-grants-1990_03
Patent number
US04908363

Reaction notes

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