HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,5-Dichloro-4,5-difluoro-2,2-bis(trifluoromethyl)-1,3-dioxolane → 4,5-Difluoro-2,2-bis(trifluoromethyl)-1,3-dioxole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,5-Dichloro-4,5-difluoro-2,2-bis(trifluoromethyl)-1,3-dioxolane | HCID 162919 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Catalyst | Titanium Tetrachloride | HCID 24193 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4,5-Difluoro-2,2-bis(trifluoromethyl)-1,3-dioxole | HCID 169957 | — |
Reaction Steps
This example was conducted in the same manner as Example 1, except that the reactants were the following: Lithium aluminum hydride (8.0 g, 0.211 mole), titanium tetrachloride (9.84 g, 0.052 mole), 4,5-dichloro-4,5-difluoro- 2,2-bis(trifluoromethyl)-1,3-dioxolane (31.5 g, 0.1 mole) and tetrahydrofuran (100 mL). The yield of this reaction was 53% with 100% conversion.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04908461 |
| Source dataset | uspto-grants-1990_03 |
| ORD ID | ord-64cf11610426429fb130829f7cf4f3c1 |
| Source note | uspto-grants-1990_03 |