4,5-Dichloro-4,5-difluoro-2,2-bis(trifluoromethyl)-1,3-dioxolane → 4,5-Difluoro-2,2-bis(trifluoromethyl)-1,3-dioxole

HRID 1165299Notes

Reaction equation

HRID 1165299 reaction equation
[H-].[Al+3].[Li+].[H-].[H-].[H-].Cl[C:8]1([F:23])[C:12](Cl)([F:13])[O:11][C:10]([C:19]([F:22])([F:21])[F:20])([C:15]([F:18])([F:17])[F:16])[O:9]1>[Ti](Cl)(Cl)(Cl)Cl.O1CCCC1>[F:13][C:12]1[O:11][C:10]([C:19]([F:20])([F:21])[F:22])([C:15]([F:16])([F:18])[F:17])[O:9][C:8]=1[F:23]

Participants

5

Reactant 2

HCID 1629194,5-Dichloro-4,5-difluoro-2,2-bis(trifluoromethyl)-1,3-dioxolaneHCID 21226445Aluminium lithium hydride

Product 1

HCID 1699574,5-Difluoro-2,2-bis(trifluoromethyl)-1,3-dioxole

Reagents, catalysts & solvents 2

HCID 24193Titanium TetrachlorideCatalystHCID 8028TetrahydrofuranSolvent

Procedure

This example was conducted in the same manner as Example 1, except that the reactants were the following: Lithium aluminum hydride (8.0 g, 0.211 mole), titanium tetrachloride (9.84 g, 0.052 mole), 4,5-dichloro-4,5-difluoro- 2,2-bis(trifluoromethyl)-1,3-dioxolane (31.5 g, 0.1 mole) and tetrahydrofuran (100 mL). The yield of this reaction was 53% with 100% conversion.

Sources & evidence

ORD record
ord-64cf11610426429fb130829f7cf4f3c1
Source dataset
uspto-grants-1990_03
Patent number
US04908461

Reaction notes

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