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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1165397Generated: October 30, 2026

Hydroxyphenylacetic acid → Ethyl 4-hydroxyphenylacetate

https://huagongshe.com/reaction/1165397

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydroxyphenylacetic acidHCID 127—
ReactantEthanolHCID 702—
ReactantSulfuric AcidHCID 1118—
ProductEthyl 4-hydroxyphenylacetateHCID 28310—

Reaction Steps

4-Hydroxyphenylacetic acid (50.0 g) is dissolved in ethanol (400 ml) and thereto is added conc. sulfuric acid (0.5 ml). The mixture is refluxed with stirring, and ethanol is distilled off to give ethyl 4-hydroxyphenylacetate (60 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04909957
Source datasetuspto-grants-1990_03
ORD IDord-675e0c6ba0dc454a96f5fe11192c2d8a
Source noteuspto-grants-1990_03