1-Chloro-4-(chloromethyl)benzene → HCID 14072292, compound

Participants

Reaction Steps

In 50 ml of N,N-dimethylformamide were dissolved 2.0 g (9.0 m mol) of 2-(4-chlorophenyl)-5-hydroxy-3(2H)-pyridazinone and 1.5 g (9.3 m mol) of p-chlorobenzyl chloride, and thereto was added 1.7 g of anhydrous potassium carbonate. The reaction mixture was heated under stirring on an oil bath at 100°-120° C. for one hour. Then, the procedure in Synthesis Example 13 were repeated to give 2.5 g of the intended compound.

Provenance & Evidence