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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1165456Generated: November 2, 2026

Pyridine → 1H-Indole-2-carboxamide

https://huagongshe.com/reaction/1165456

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridineHCID 1049—
Reactant1H-indole-2-carbonyl ChlorideHCID 11816208—
SolventDichloromethaneHCID 6344—
Product1H-Indole-2-carboxamideHCID 594832—

Reaction Steps

Indolyl carboxylic acid amides as starting materials may be produced by reacting an indolyl carboxylic acid chloride in absolute methylene chloride with an amine in the presence of pyridine at -10° to 0°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04910207
Source datasetuspto-grants-1990_03
ORD IDord-5e960840b0ed410082e2453f62e812e4
Source noteuspto-grants-1990_03